| WNCAAB | 11/09 23:00 | - | [324] USC Upstate - Feminin v East Carolina - Feminin [76] | L | 35-105 | |
| WNCAAB | 11/08 00:00 | - | [149] USC Upstate - Feminin v Davidson - Feminin [149] | L | 51-86 | |
| WNCAAB | 03/02 23:00 | 3 | [282] USC Upstate - Feminin v High Point - Feminin [162] | L | 43-50 | |
| WNCAAB | 03/01 19:30 | 7 | [344] Charleston Southern - Feminin v USC Upstate - Feminin [281] | W | 48-65 | |
| WNCAAB | 02/25 19:00 | - | [276] USC Upstate - Feminin v Gardner Webb - Feminin [9] | L | 59-83 | |
| WNCAAB | 02/23 00:00 | - | [219] Presbyterian - Feminin v USC Upstate - Feminin [289] | W | 56-61 | |
| WNCAAB | 02/18 20:00 | - | [168] High Point - Feminin v USC Upstate - Feminin [284] | L | 83-51 | |
| WNCAAB | 02/16 00:00 | - | [274] USC Upstate - Feminin v Longwood - Feminin [324] | L | 64-97 | |
| WNCAAB | 02/12 19:00 | - | [271] USC Upstate - Feminin v Winthrop - Feminin [303] | L | 52-56 | |
| WNCAAB | 02/11 21:00 | - | [314] Winthrop - Feminin v USC Upstate - Feminin [262] | L | 53-48 | |
| WNCAAB | 02/08 23:00 | - | [276] USC Upstate - Feminin v Charleston Southern - Feminin [339] | W | 71-67 | |
| WNCAAB | 02/04 19:00 | - | [267] USC Upstate - Feminin v UNC Asheville - Feminin [295] | L | 65-68 | |
| WNCAAB | 02/02 00:00 | - | [146] Campbell - Feminin v USC Upstate - Feminin [254] | L | 57-51 | |
| WNCAAB | 01/28 19:00 | - | [242] USC Upstate - Feminin v Radford - Feminin [246] | L | 39-59 | |
| WNCAAB | 01/26 00:00 | - | [35] Gardner Webb - Feminin v USC Upstate - Feminin [218] | L | 81-56 | |
| WNCAAB | 01/21 20:00 | - | [287] UNC Asheville - Feminin v USC Upstate - Feminin [237] | W | 55-66 | |
| WNCAAB | 01/18 23:30 | - | [229] USC Upstate - Feminin v Presbyterian - Feminin [239] | L | 53-82 | |
| WNCAAB | 01/14 20:00 | - | [334] Longwood - Feminin v USC Upstate - Feminin [254] | W | 42-55 | |
| WNCAAB | 01/12 00:00 | - | [237] USC Upstate - Feminin v Campbell - Feminin [171] | L | 49-51 | |
| WNCAAB | 01/07 19:00 | - | [255] USC Upstate - Feminin v High Point - Feminin [289] | W | 62-60 | |
| WNCAAB | 01/05 00:00 | - | [248] Radford - Feminin v USC Upstate - Feminin [281] | W | 49-55 | |
| WNCAAB | 12/31 20:00 | - | [332] Charleston Southern - Feminin v USC Upstate - Feminin [299] | W | 57-59 | |
| WNCAAB | 12/29 22:00 | - | Winthrop - Feminin v USC Upstate - Feminin | - | Cancelled | |
| WNCAAB | 12/20 20:00 | - | Queens - Feminin v USC Upstate - Feminin | L | 69-48 | |
| WNCAAB | 12/16 23:00 | - | [278] USC Upstate - Feminin v North Carolina - Feminin [39] | L | 47-89 | |
| WNCAAB | 12/15 00:00 | - | USC Upstate - Feminin v Montreat - Feminin | W | 60-41 | |
| WNCAAB | 12/12 16:00 | - | [227] Morehead State - Feminin v USC Upstate - Feminin [321] | W | 59-64 | |
| WNCAAB | 12/03 20:00 | - | [169] Old Dominion - Feminin v USC Upstate - Feminin [319] | L | 57-31 | |
| WNCAAB | 11/30 00:30 | - | [309] USC Upstate - Feminin v Vanderbilt - Feminin [103] | L | 45-74 | |
| WNCAAB | 11/23 22:00 | - | [300] USC Upstate - Feminin v UNC Greensboro - Feminin [198] | L | 48-54 |