[2] BUF Sabres 1-2 NJ Devils [12] 2021-10-23 23:00
Stadium: Prudential Center
Home Manager: Lindy Ruff Away Manager: Don Granato
Head to Head
| NHL | 2021/04/08 23:00 | NJ Devils v BUF Sabres | L | 6-3 |
| NHL | 2021/04/06 23:00 | BUF Sabres v NJ Devils | W | 5-3 |
| NHL | 2021/03/16 23:00 | BUF Sabres v NJ Devils | L | 2-3 |
| NHL | 2021/02/26 00:00 | NJ Devils v BUF Sabres | L | 4-3 |
| NHL | 2021/02/24 00:00 | BUF Sabres v NJ Devils | W | 4-1 |
| NHL | 2021/02/20 17:30 | BUF Sabres v NJ Devils | W | 3-2 |
| NHL | 2021/01/31 18:00 | NJ Devils v BUF Sabres | L | 5-3 |
| NHL | 2021/01/30 18:00 | NJ Devils v BUF Sabres | W | 3-4 |
| NHL | 2019/12/03 00:00 | NJ Devils v BUF Sabres | W | 1-7 |
| NHL | 2019/10/05 23:00 | NJ Devils v BUF Sabres | W | 2-7 |
| NHL | 2019/03/25 23:00 | BUF Sabres v NJ Devils | L | 1-3 |
| NHL | 2019/02/17 23:00 | BUF Sabres v NJ Devils | L | 1-4 |
| NHL | 2019/01/09 00:00 | NJ Devils v BUF Sabres | W | 1-5 |
| NHL | 2018/01/31 00:00 | BUF Sabres v NJ Devils | L | 1-3 |
| NHL | 2018/01/30 16:05 | NJ Devils v BUF Sabres | L | 3-1 |
| NHL | 2017/12/30 00:00 | BUF Sabres v NJ Devils | W | 4-3 |
| NHL | 2017/10/09 19:00 | NJ Devils v BUF Sabres | L | 6-2 |
| NHL | 2017/02/07 00:00 | BUF Sabres v NJ Devils | L | 1-2 |
| NHL | 2016/11/13 00:00 | BUF Sabres v NJ Devils | L | 2-4 |
| NHL | 2016/11/12 00:00 | NJ Devils v BUF Sabres | L | 2-1 |