[1] Club America 1-0 Tigres UANL [3] 2021-10-24 00:00
Stadium: Estadio Azteca Round: 15
Referee: Fernando Guerrero Ramirez Home Manager: Santiago Hernan Solari Poggio Away Manager: Miguel Herrera
Head to Head
| Europa - Amicale | 2021/07/10 19:07 | Tigres UANL v Club America | W | 0-1 |
| Mexic - Liga MX | 2021/04/11 02:05 | Tigres UANL v Club America | W | 1-3 |
| Mexic - Liga MX | 2020/11/01 23:30 | Club America v Tigres UANL | W | 3-1 |
| Mexic - Liga MX | 2020/01/19 03:00 | Club America v Tigres UANL | W | 1-0 |
| Mexic - Liga MX | 2019/12/02 03:00 | Tigres UANL v Club America | W | 2-4 |
| Mexic - Liga MX | 2019/11/29 03:00 | Club America v Tigres UANL | L | 1-2 |
| Mexic - Liga MX | 2019/08/25 02:05 | Tigres UANL v Club America | D | 1-1 |
| Leagues Cup | 2019/08/21 00:30 | Club America v Tigres UANL | L | 5-7 |
| Mexic - Champion of Champions | 2019/07/15 01:15 | Club America v Tigres UANL | W | 6-5 |
| Mexic - Liga MX | 2019/03/31 01:00 | Club America v Tigres UANL | W | 3-0 |
| Mexic - Liga MX | 2018/10/07 00:00 | Tigres UANL v Club America | W | 2-3 |
| Mexic - Liga MX | 2018/02/11 01:00 | Tigres UANL v Club America | D | 1-1 |
| Mexic - Liga MX | 2017/12/03 01:00 | Tigres UANL v Club America | L | 3-0 |
| Mexic - Liga MX | 2017/11/30 03:00 | Club America v Tigres UANL | L | 0-1 |
| Mexic - Liga MX | 2017/08/24 00:00 | Club America v Tigres UANL | D | 2-2 |
| Mexic - Liga MX | 2017/01/22 01:00 | Tigres UANL v Club America | L | 4-2 |
| Mexic - Liga MX | 2016/12/26 00:30 | Tigres UANL v Club America | L | 4-1 |
| Mexic - Liga MX | 2016/12/23 03:00 | Club America v Tigres UANL | D | 1-1 |
| Mexic - Liga MX | 2016/07/31 02:00 | Club America v Tigres UANL | L | 0-3 |
| CONCACAF Champions Cup | 2016/04/28 01:45 | Club America v Tigres UANL | W | 2-1 |
| CONCACAF Champions Cup | 2016/04/21 01:45 | Tigres UANL v Club America | W | 0-2 |
| Meciuri amicale internationale intercluburi | 2016/03/26 20:00 | Club America v Tigres UANL | L | 2-3 |
| Mexic - Liga MX | 2016/02/28 01:00 | Tigres UANL v Club America | L | 4-1 |
| Mexic - Liga MX | 2015/09/12 22:00 | Club America v Tigres UANL | L | 0-1 |
| Mexic - Liga MX | 2015/01/31 23:00 | Club America v Tigres UANL | W | 1-0 |
| Mexic - Liga MX | 2014/12/15 00:00 | Club America v Tigres UANL | W | 3-0 |
| Mexic - Liga MX | 2014/12/12 02:30 | Tigres UANL v Club America | L | 1-0 |
| Mexic - Liga MX | 2014/08/10 00:00 | Tigres UANL v Club America | W | 0-2 |