| Uruguay - Liga de Rezerve | 2022/06/06 18:00 | Atletico Fenix - Rezerve v Rentistas - Rezerve | D | 0-0 |
| Uruguay - Liga de Rezerve | 2022/05/31 18:00 | Rentistas - Rezerve v Cerro Largo - Rezerve | L | 0-2 |
| Uruguay - Liga de Rezerve | 2022/05/24 13:00 | Atletico River Plate Reserves v Rentistas - Rezerve | L | 2-1 |
| Uruguay - Liga de Rezerve | 2022/05/19 18:00 | Rentistas - Rezerve v Boston River - Rezerve | W | 3-2 |
| Uruguay - Liga de Rezerve | 2022/05/10 13:30 | Plaza Colonia - Rezerve v Rentistas - Rezerve | W | 1-2 |
| Uruguay - Liga de Rezerve | 2022/05/02 18:00 | Rentistas - Rezerve v Montevideo Wanderers - Rezerve | L | 0-1 |
| Uruguay - Liga de Rezerve | 2022/04/05 19:00 | Rentistas - Rezerve v Penarol - Rezerve | D | 1-1 |
| Uruguay - Liga de Rezerve | 2022/03/28 19:00 | Liverpool Montevideo - Rezerve v Rentistas - Rezerve | L | 3-2 |
| Uruguay - Liga de Rezerve | 2022/06/06 18:00 | Defensor Sporting - Rezerve v Deportivo Maldonado - Rezerve | D | 1-1 |
| Uruguay - Liga de Rezerve | 2022/05/31 18:00 | Danubio - Rezerve v Defensor Sporting - Rezerve | W | 0-3 |
| Uruguay - Liga de Rezerve | 2022/05/26 17:00 | Albion FC - Rezerve v Defensor Sporting - Rezerve | L | 1-0 |
| Uruguay - Liga de Rezerve | 2022/05/24 17:00 | Defensor Sporting - Rezerve v Nacional de Montevideo - Rezerve | L | 1-3 |
| Uruguay - Liga de Rezerve | 2022/05/10 18:00 | Defensor Sporting - Rezerve v Cerrito - Rezerve | W | 3-1 |
| Uruguay - Liga de Rezerve | 2022/05/02 18:00 | Defensor Sporting - Rezerve v Atletico Fenix - Rezerve | L | 0-2 |
| Uruguay - Liga de Rezerve | 2022/04/05 19:00 | Defensor Sporting - Rezerve v Atletico River Plate Reserves | L | 0-2 |
| Uruguay - Liga de Rezerve | 2022/03/29 19:00 | Boston River - Rezerve v Defensor Sporting - Rezerve | D | 1-1 |