[5] Brighton U23 2-1 Crystal Palace U23 [8] 2021-10-16 16:00
Stadium: American Express Community Stadium Round: 1
Home History
| Anglia - Premier League 2 | 2021/10/01 18:00 | Arsenal U23 v Brighton U23 | L | 3-0 |
| Anglia - Premier League 2 | 2021/09/24 18:00 | Brighton U23 v Leicester U23 | W | 2-1 |
| Anglia - Premier League 2 | 2021/09/18 11:00 | Man Utd U23 v Brighton U23 | L | 2-1 |
| Anglia - Premier League 2 | 2021/09/10 18:00 | Brighton U23 v Blackburn U23 | W | 4-1 |
| Anglia - Premier League 2 | 2021/08/28 12:00 | Liverpool U23 v Brighton U23 | D | 1-1 |
| Anglia - Premier League 2 | 2021/08/20 18:00 | Brighton U23 v West Ham U23 | W | 4-2 |
| Anglia - Premier League 2 | 2021/08/16 18:00 | Derby U23 v Brighton U23 | W | 0-2 |
| Anglia - Premier League 2 | 2021/04/24 11:00 | Everton U23 v Brighton U23 | D | 1-1 |
Away History
| Anglia - Premier League 2 | 2021/10/01 12:00 | Crystal Palace U23 v Tottenham U23 | W | 4-3 |
| Anglia - Premier League 2 | 2021/09/24 18:00 | West Ham U23 v Crystal Palace U23 | L | 1-0 |
| Anglia - Premier League 2 | 2021/09/18 14:00 | Man City U23 v Crystal Palace U23 | L | 4-2 |
| Anglia - Premier League 2 | 2021/09/13 18:00 | Leicester U23 v Crystal Palace U23 | W | 1-6 |
| Anglia - Premier League 2 | 2021/08/27 18:00 | Crystal Palace U23 v Everton U23 | W | 3-1 |
| Anglia - Premier League 2 | 2021/08/20 18:00 | Arsenal U23 v Crystal Palace U23 | L | 4-2 |
| Anglia - Premier League 2 | 2021/08/16 18:00 | Crystal Palace U23 v Leeds U23 | L | 1-3 |
| Europa - Amicale | 2021/07/23 18:00 | Stevenage v Crystal Palace U23 | L | 1-0 |